Physicochemical, Thermal and Spectroscopic Characterization of Sodium Selenate Using XRD, PSD, DSC, TGA/DTG, UV-vis, and FT-IR

By Mahendra Kumar Trivedi1, Kalyan Kumar Sethi2, Parthasarathi Panda2, Snehasis Jana2

1. Trivedi Global Inc. 2. Trivedi Science Research Laboratory Pvt. Ltd.

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Abstract

Sodium selenate is an important inorganic compound, but lacks reliable and accurate physico-chemical and spectral characterization information. This article described the in-depth physicochemical, thermal, and spectroscopic characterization of sodium selenate using various analytical techniques. The powder X-ray diffractogram showed well-defined, narrow and sharp peaks indicating that sodium selenate is crystalline in nature. The crystallite size was found to be in the range of 28.75 to 49.97 nm. The average particle size was found to be of 3.93 (d10), 14.44 (d50), and 40.65 (d90) µm with an average surface area of 0.676 m2/g. The differential scanning calorimetry showed the endothermic inflation at 588.81 °C with the latent heat of fusion 103 J/g. The thermogravimetric analysis revealed two steps of the thermal degradation process. Similarly, the differential thermogravimetric analysis exhibited the major peaks in the thermogram and disclosed Tmax at 852.65 °C. This indicated sodium selenate thermally more stable in nature. The UV-visible spectrum showed maximum absorbance at 205.1 nm (λmax). The Fourier transform infrared spectrum showed a peak at 888 cm-1 due to the Se-O stretching. These information would be very much useful in the field of nutraceuticals/ pharmaceuticals and other industries using sodium selenate as an ingredient.

References

1. Martens DA. Selenium. In: Encyclopedia of Water Science. United States Department of Agriculture (USDA), Tucson, Arizona, USA. 2003.

2. Stadlober M, Sager M, Irgolic K. Identification and quantification of selenium compounds in sodium selenite supplemented feeds by HPLC-ICP-MS. Die Bodenkultur 2001; 52: 233-41.

3. Ganther HE, Baumann CA. Selenium metabolism. II. Modifying effects of sulfate. J Nutr 1962; 77: 408-14.

4. Cardoso BR, Ong TP, Jacob-Filho W, Jaluul O, Freitas MI, Cozzolino SM. Nutritional status of selenium in Alzheimer’s disease patients. Br J Nutr 2010;103: 803-6.

5. Chen J, Berry MJ. Selenium and selenoproteins in the brain and brain diseases. J Neurochem 2003; 86: 1-12.

6. Ani M, Moshtaghie AA, Aghadavod M. Protective effects of selenium and zinc on the brain acetylcholinesterase activity in lead intoxified rat. Res Pharm Sci 2007; 2: 80-4.

7. Abubakar MG, Taylor A, Ferns GA. The effects of aluminium and selenium supplementation on brain and liver antioxidant status in the rat. Afr J Biotechnol 2004; 3: 88-93.

8. Fleet JC. Dietary selenium repletion may reduce cancer incidence in people at high risk who live in areas with low soil selenium. Nutr Rev 1997; 55: 277-9.

9. Krieger RI. Handbook of pesticide toxicology, 2nd edition, volume 1. Academic Press. San Diego. 2001, pp. 1908.

10. Hanson B, Lindblom SD, Loeffler ML, Pilon-Smits EAH. Selenium protects plants from phloem-feeding aphids due to both deterrence and toxicity. New Phytol 2004; 162: 655-62.

11. Barceloux DG, Barceloux D. Selenium. J Toxicol Clin Toxicol 1999; 37: 145-72.

12. Thomson CD, Robinson MF. Urinary and fecal excretions and absorption of a large supplement of selenium: Superiority of selenate over selenite. Am J Clin Nutr 1986; 44: 659-63.

13. Salama RM, Schaalan MF, Elkoussi AA, Khalifa AE. Potential utility of sodium selenate as an adjunct to metformin in treating type II diabetes mellitus in rats: A perspective on protein tyrosine phosphatase. Biomed Res Int 2013; 231378.

14. Chereson R. Bioavailability, bioequivalence, and drug selection. In: Basic pharmacokinetics, 1st edition. Editors: Makoid CM, Vuchetich PJ, Banakar UV Pharmaceutical Press. London. 2009.

15. Langford JI, Wilson AJC. Scherrer after sixty years: A survey and some new results in the determination of crystallite size. J Appl Cryst 1978; 11: 102-13.

16. Buhrke VE, Jenkins R, Smith DK. Preparation of specimens for X-ray fluorescence and X-ray diffraction analysis. John Wiley & Sons Inc. New York. 1998, pp. 148.

17. Burgess DJ, Duffy E, Etzler F, Hickey AJ. Particle size analysis: AAPS workshop report, cosponsored by the Food and Drug Administration and the United States Pharmacopeia. AAPS J 2004; 6: 23-34.

18. Weiner BB. What is a continuous particle size distribution? Brookhaven Instruments, NY, USA. 2011.

19. Wolfrom RL The language of particle size. J GXP Compliance 2011; 15: 10-20.

20. Balzar D, Audebrand, Daymond MR, Fitch A, Hewat A, Langford JI, Le Bail A, Louër D, Masson O, McCowan CN, Popa NC, Stephens PW, Toby HB. Size-strain line-broadening analysis of the ceria round-robin sample. J Appl Cryst 2004; 37: 911-24.

21. Swanson HE, McMurdie HF, Evans MCME, Paretzkin B, DeGroot JH, Carmel SJ.Standard X-Ray Diffraction Powder Patterns. National Bureau of Standards Monograph-25, Section 9, Nat Bur Stand 1971. pp. 55.

22. Moore DM, Reynolds Jr RC. X-Ray diffraction and the identification and analysis of clay mineral, 2nd edition. Oxford University Press. New York. 1997.

23. Sardela M. X-ray Analysis Methods. Advanced Materials Characterization Workshop, The Frederick Seitz Materials Research Laboratory-University of Illinois at Urbana-Champaign. 2008.

24. Martin AN, Patrick JS. Martin’s physical pharmacy and pharmaceutical sciences: Physical chemical and biopharmaceutical principles in the pharmaceutical sciences. Phila: Lippincott Williams and Wilkins. 2006.

25. Jones AT. Development of the γ-crystal form in random copolymers of propylene and their analysis by DSC and X-ray methods. Polymer 1971; 12: 487-508.

26. Martin FJ, Albers H, Lambeck PV, Van de Velde GMH, Popma ThJA. Luminescent thin films by the chemical aerosol deposition technology (CADT). J Aerosol Sci 1991; 22: 435-8.

27. Bajaj S, Singla D, Sakhuja N. Stability testing of pharmaceutical products. J Appl Pharm Sci 2012; 2: 129-38.

28. Bansal KR. Synthetic Approaches in Organic Chemistry. Jones & Bartlett Publishers International. 1998, pp. 236.

29. Miller FA, Wilkins CH. Infrared spectra and characteristic frequencies of inorganic ions their use in qualitative analysis. Anal Chem 1952; 24: 1281.

Cite this work

Researchers should cite this work as follows:

  • Mahendra Kumar Trivedi; Kalyan Kumar Sethi; Parthasarathi Panda; Snehasis Jana (2019), "Physicochemical, Thermal and Spectroscopic Characterization of Sodium Selenate Using XRD, PSD, DSC, TGA/DTG, UV-vis, and FT-IR," https://diagrid.org/resources/1875.

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